Ipamorelin research: what the studies have looked at
This page summarises the published research on ipamorelin, for reference. It states what each study investigated and in what model, not an effect in people, and it is not medical advice. Ipamorelin is not an approved medicine; what we supply is a research chemical for laboratory use only.
What ipamorelin is
Ipamorelin is a synthetic pentapeptide described as a growth-hormone secretagogue: it acts on the ghrelin receptor (GHS-R1a) rather than the GHRH receptor. Most of the published work is preclinical, in cells and animals, with a small amount of early human pharmacokinetic data. It has not been approved as a drug anywhere.
What the studies investigated
Raun et al. (1998), European Journal of Endocrinology 139(5):552-561. In vitro, rat and swine. Characterised ipamorelin and reported growth-hormone release without a rise in ACTH or cortisol in the models used Source.
Gobburu et al. (1999), Pharmaceutical Research 16(9):1412-1416. Human, pharmacokinetic and pharmacodynamic. Investigated the pharmacokinetics of ipamorelin and the GH response, reporting a half-life of about two hours Source.
Svensson et al. (2000), Journal of Endocrinology 165(3):569-577. Rat. Investigated the effect of ipamorelin on bone mineral content Source.
Mechanism, as described in the literature
The literature describes ipamorelin as a selective ghrelin-receptor agonist that prompts growth-hormone release, and the early work is notable for reporting little effect on cortisol or prolactin in the animal models used. The human data is limited to pharmacokinetics and the GH response, not clinical endpoints, and the rest is preclinical.
The material we supply
We supply ipamorelin as a research chemical, released against a written specification with a batch certificate of analysis. It is not a medicine and is not for human or animal use. For the vial sizes, the price per mg and how to order, see the ipamorelin compound page; the COA lookup pulls the certificate for any batch. The references above link to each study’s record; this summary is for research and educational reference only.